| Bioactivity | ALKBH5-IN-3 (Compound 20m) is a potent and selective ALKBH5 inhibitor, with an IC50 of 21 nM. ALKBH5-IN-3 could efficiently stabilize ALKBH5 in HepG2 cells and increase m6A level in intact cells[1]. |
| Target | IC50: 21 nM (ALKBH5) |
| CAS | 1505579-77-0 |
| Formula | C11H7F3N2O3 |
| Molar Mass | 272.18 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fang Z, et, al. Discovery of a potent, selective and cell active inhibitor of m6A demethylase ALKBH5. Eur J Med Chem. 2022 Aug 5:238:114446. |
ALKBH5-IN-3
CAS: 1505579-77-0 F: C11H7F3N2O3 W: 272.18
ALKBH5-IN-3 (Compound 20m) is a potent and selective ALKBH5 inhibitor, with an IC50 of 21 nM. ALKBH5-IN-3 could efficien
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