| Bioactivity | ALK5-IN-80 (Compound 29b) is a selective ALK5 inhibitor with an IC50 value of 3.7 nM. ALK5-IN-80 can be used for cancer research[1]. |
| Target | IC50: 3.7 nM (ALK5), 73.7 nM (ALK1), 183 nM (ALK2), >10000 nM (ALK3), 3690 nM (ALK4), >10000 nM (ALK6), 6344 nM (ACTR2B) |
| Formula | C21H18FN7O2S |
| Molar Mass | 451.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Arai M, et al. Design and synthesis of novel thiazole-derivatives as potent ALK5 inhibitors. Bioorg Med Chem Lett. 2024 May 16;108:129797. |