| Bioactivity | ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 with an IC50 value ≤10 nM. ALK5-IN-26 can be used for the research of cancer[1]. |
| Target | IC50: ≤10 nM (ALK5) |
| Invitro | ALK5-IN-26 (0-1 μM; 24 h) inhibits ALK5 with an IC50 value ≤10 nM, and shows selectivity of ALK2 IC50/ALK5 IC50 of a ratio ＜100[1]. |
| Name | ALK5-IN-26 |
| CAS | 2785430-82-0 |
| Formula | C24H25FN8 |
| Molar Mass | 444.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Franz B, et al. ALK-5 INHIBITORS AND USES THEREOF. WO/2022/126133 A1. 2022. |