| Bioactivity | ALK/ROS1-IN-3 (compound C01) is a ROS1 and ALK dual inhibitor with IC50s of 42.3 nM and 49.1 nM for ROS1G2032R and ALKG1202R, respectively[1]. |
| Name | ALK/ROS1-IN-3 |
| Formula | C32H32N4O2 |
| Molar Mass | 504.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Siming Liu, et al. Discovery of novel 2-aminopyridine derivatives as ROS1 and ALK dual inhibitors to combat drug-resistant mutants including ROS1G2032R and ALKG1202R. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2227779. |