| Bioactivity | ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK), with an IC50 of 2.9 nM[1]. |
| Target | IC50: 2.9 nM (ALK) |
| Invitro | ALK-IN-5 potently inhibits ALK with cellular IC50 of 27 nM[1]. |
| Name | ALK-IN-5 |
| CAS | 2351929-66-1 |
| Formula | C24H25FN6O3 |
| Molar Mass | 464.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fushimi M, et al. Discovery of Potent, Selective, and Brain-Penetrant 1 H-Pyrazol-5-yl-1 H-pyrrolo[2,3- b]pyridines as Anaplastic Lymphoma Kinase (ALK) Inhibitors. J Med Chem. 2019 May 23;62(10):4915-4935. |
ALK-IN-5
CAS: 2351929-66-1 F: C24H25FN6O3 W: 464.49
ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK), with an IC50 of 2.9
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.