| Bioactivity | ALDH2 modulator 1 is a potent and orally active aldehyde dehydrogenase-2 (ALDH2) modulator. ALDH2 modulator 1 reduces blood alcohol levels in mice[1]. |
| In Vivo | ALDH2 modulator 1 (compound 161) (10 mg/kg for i.v.; 40, 60 mg/kg for p.o.) 降低经口服 5 g/kg 酒精处理的小鼠的血液酒精水平[1]。 Animal Model: |
| Name | ALDH2 modulator 1 |
| CAS | 1629615-99-1 |
| Formula | C18H18ClFN2O3 |
| Molar Mass | 364.80 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wenjin Yang, et al. Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof. WO2014160185A2. |