| Bioactivity | AKT-IN-3 (compound E22) is a potent, orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK. AKT-IN-3 (compound E22) induces apoptosis and inhibits metastasis of cancer cells[1]. | ||||||||||||
| Name | AKT-IN-3 | ||||||||||||
| CAS | 2374740-21-1 | ||||||||||||
| Formula | C23H23Cl2F2N5O3 | ||||||||||||
| Molar Mass | 526.36 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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AKT-IN-3
CAS: 2374740-21-1 F: C23H23Cl2F2N5O3 W: 526.36
AKT-IN-3 (compound E22) is a potent, orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for A
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