| Bioactivity | AKT-IN-18, an inhibitor of Akt, inhibits Akt with an IC50 of 69.45 μΜ in A549 cells. AKT-IN-18 induces apoptosis and can be used in non-small cell lung cancer study[1]. |
| Invitro | AKT-IN-18 (Compound 3i) (0-500 μM；24 小时) 对 A549 细胞具有细胞毒性，并诱导细胞凋亡[1]。 Apoptosis Analysis[1] Cell Line: |
| Name | AKT-IN-18 |
| Formula | C19H14ClN5O2S |
| Molar Mass | 411.86 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Erdönmez B,et.al. Design, Synthesis, and Evaluation of a New Series of Hydrazones as Small-Molecule Akt Inhibitors for NSCLC Therapy. ACS Omega. 2023 May 24;8(22):20056-20065. |