| Bioactivity | AKR1C3-IN-7 (Compound 13) is a potent, selective AKR1C3 inhibitor with an IC50 of 0.19 μM. AKR1C3-IN-7 shows antitumor activity[1]. |
| Target | IC50: 0.19 μM (AKR1C3) |
| Invitro | AKR1C3-IN-7 (Compound 13) shows antiproliferative activity with an IC50 of 54.81 ± 2.47 μM against prostate cancer cell line 22rv1[1]. |
| Name | AKR1C3-IN-7 |
| Formula | C24H20N2O4 |
| Molar Mass | 400.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pippione AC, et al. New aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the hydroxytriazole scaffold. Eur J Med Chem. 2022 Jul 5;237:114366. |