Bioactivity | AK59 is a STING degrader that works by leveraging HERC4, a hect domain E3 ligase. AK59 can be used in the study of autoimmune diseases and cancer[1]. |
Formula | C21H14F3N3O2S |
Molar Mass | 429.41 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mutlu M, et al. Small molecule induced STING degradation facilitated by the HECT ligase HERC4. Nat Commun. 2024 May 29;15(1):4584. |