| Bioactivity | AIP-II is a macrocyclic peptide signaling molecule used for quorum sensing, which can be produced be Staphylococcus aureus. AIP-II binds to AgrC-II receptor, regulates the virulence gene expression in Staphylococcus aureus. AIP-II is an antagonist for AgrC-I receptor[1]. |
| CAS | 200010-31-7 |
| Sequence | Gly-Val-Asn-Ala-Cys-Ser-Ser-Leu-Phe (sulfide bridge: Cys5-Phe9) |
| Shortening | GVNACSSLF (sulfide bridge: Cys5-Phe9) |
| Formula | C38H58N10O12S |
| Molar Mass | 878.99 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tal-Gan Y, et al., Structural characterization of native autoinducing peptides and abiotic analogues reveals key features essential for activation and inhibition of an AgrC quorum sensing receptor in Staphylococcus aureus. J Am Chem Soc. 2013 Dec 11;135(49):18436-44. |
AIP-II
CAS: 200010-31-7 F: C38H58N10O12S W: 878.99
AIP-II is a macrocyclic peptide signaling molecule used for quorum sensing, which can be produced be Staphylococcus aure
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