AICAR-13C2,15N_product_DataBase

Bioactivity	AICAR-13C2,15N (Acadesine-13C2,15N; AICA Riboside-13C2,15N)is the 13C and 15N labeledAICAR(HY-13417)[1]. AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor[2][3].
Invitro	氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。
Name	AICAR-13C2,15N
CAS	1609374-70-0
Formula	C713C2H14N315NO5
Molar Mass	261.21
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

PeptideDB