| Bioactivity | AI-4-57 is an allosteric inhibitor for CBFβ SMMHC-RUNX1 interaction with an IC50 of 22 μM[1]. |
| CAS | 63053-14-5 |
| Formula | C13H11N3O |
| Molar Mass | 225.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Illendula A, et al., A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice. Science. 2015 Feb 13;347(6223):779-84. |