| Bioactivity | AI-10-104 is an inhibitor for runt-related transcription factor (RUNX), which enhances the cytotoxicity in myeloma cells[1]. |
| Invitro | AI-10-104 (0-10 μM) 通过解离 RUNXs-IKZFs 复合物抑制 RUNX，增强来那度胺 (CC-5013) 的抗增殖作用及其对骨髓瘤细胞的细胞毒性[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> AI-10-104 相关抗体: Western Blot Analysis[1] Cell Line: |
| CAS | 1881276-00-1 |
| Formula | C14H10F3N3O2 |
| Molar Mass | 309.24 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhou N, et al., RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation. Leukemia. 2019 Aug;33(8):2006-2021. |
AI-10-104
CAS: 1881276-00-1 F: C14H10F3N3O2 W: 309.24
AI-10-104 is an inhibitor for runt-related transcription factor (RUNX), which enhances the cytotoxicity in myeloma cells
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.