Bioactivity | AHR-1911 (10-Undecen-1-yl-Thiopseudourea Iodide;Isothiuronium) is a thiourea-based anti-inflammatory and anti-tumor agent that has an improving effect on burned skin. AHR-1911 produces histamine-like effects when injected intradermally and may reduce arterial pressure in anesthetized dogs. AHR-1911 inhibits tumor growth and reduces microsomal and C-polysome protein synthesis[1][2]. |
CAS | 22584-04-9 |
Formula | C12H25IN2S |
Molar Mass | 356.31 |
Appearance | 固体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
Reference | [1]. Fuenmayor L, et al. Effect of 10 undecen 1-YL thiopseudourea iodide (AHR-1911) on rat arterial pressure and capillary permeability. Proc Soc Exp Biol Med. 1973 Jun;143(2):568-71. [2]. González-Cadavid NF, et al. Inhibition of translation in liver polyribosomes by a new substituted thiopseudourea with antitumour action. Biochem J. 1974 Feb;138(2):129-41. |