| Bioactivity | AGN 191976 is a potent and selective thromboxane A2-sensitive (TP) receptor agonist with EC50 values of 0.23 nM and 24 nM in rat aorta and human platelets, respectively. AGN 191976 has potent IOP-lowering effects in dogs and monkeys. AGN 191976 can be used to study vascular biology and the role of thromboxane A2 in vascular function[1]. |
| CAS | 159359-94-1 |
| Formula | C21H32O6 |
| Molar Mass | 380.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. KRAUSS, et al. "AGN 191976: a novel thromboxane A2-mimetic with ocular hypotensive properties." Journal of ocular pharmacology and therapeutics 11.3 (1995): 203-212. |