| Bioactivity | AGG-523 (PF-5212371) is a reversible, non-hydroxamate, zinc-binding selective aggrecanase 1 (ADAMTS4) and aggrecanase 2 (ADAMTS5) inhibitor. AGG-523 can be used for the study of osteoarthritis (OA)[1]. |
| CAS | 920289-29-8 |
| Formula | C28H29FN2O4 |
| Molar Mass | 476.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wang K, et al. Investigational drugs for the treatment of osteoarthritis. Expert Opin Investig Drugs. 2015;24(12):1539-56. |