| Bioactivity | AGDV is the γ chain of fibrinogen. AGDV is critical for platelet aggregation[1][2]. |
| Invitro | AGDV (50 μM) inhibits platelet adherence by 40.2%[1].AGDV does not inhibit fibrinogen binding to ADP-stimulated platelets[2]. |
| Name | AGDV |
| CAS | 99896-90-9 |
| Shortening | AGDV |
| Formula | C14H24N4O7 |
| Molar Mass | 360.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lawrence JB, et al. Arginine-glycine-aspartic acid- and fibrinogen gamma-chain carboxyterminal peptides inhibit platelet adherence to arterial subendothelium at high wall shear rates. An effect dissociable from interference with adhesive protein binding. J Clin Invest. 1990 Nov;86(5):1715-22. [2]. Plow EF, et al. The effect of Arg-Gly-Asp-containing peptides on fibrinogen and von Willebrand factor binding to platelets. Proc Natl Acad Sci U S A. 1985 Dec;82(23):8057-61. |