| Bioactivity | AG6033 is a potential novel CRBN modulator. AG6033 suppresses various tumor cells by modulating the interactions between CRBN and various antitumor target proteins. AG6033 can cause GSPT1 and IKZF1 degradation. AG6033 induces CRBN-dependent cytotoxic effect[1]. |
| Invitro | AG6033 (0.064-40 μM, 4 h) has potent inhibition ability against A549[1].AG6033 (1-10 μM, 24 h) significantly promotes apoptosis of A549 cells in a dose-dependent manner[1]. Cell Proliferation Assay Cell Line: |
| Name | AG6033 |
| CAS | 329706-62-9 |
| Formula | C30H23N5O4 |
| Molar Mass | 517.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |