Bioactivity | AG-7404 is an inhibitor of picornaviral 3C protease, with anti-poliovirus activity (EC50=0.080-0.674 μM). AG-7404 has synergy with V-073 (HY-104074) or BTA798 (HY-106254), and fully inhibits all V-073-resistant variants[1]. |
Name | AG-7404 |
CAS | 343565-99-1 |
Formula | C26H29N5O7 |
Molar Mass | 523.54 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Rhoden E,et al. Anti-poliovirus activity of protease inhibitor AG-7404, and assessment of in vitro activity in combination with antiviral capsid inhibitor compounds. Antiviral Res. 2013 May;98(2):186-91. |