| Bioactivity | AG-041R is a potent and selective CCK2 Receptor/Gastrin antagonist. AG-041R inhibits gastrin-evoked secretion of pancreastatin with an IC50 of 2.2 nM. AG-041R inhibits cell growth of Mastomys ECL carcinoid tumor cells[1][2]. |
| CAS | 159883-95-1 |
| Formula | C31H36N4O5 |
| Molar Mass | 544.64 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ding XQ, et al. Evaluation of three novel cholecystokinin-B/gastrin receptor antagonists: a study of their effects on rat stomach enterochromaffin-like cell activity. Pharmacol Toxicol. 1997 Nov;81(5):232-7. [2]. Lindström, E., et al. Pharmacological analysis of CCK2 receptor antagonists using isolated rat stomach ECL cells. Br. J. Pharmacol. 127(2), 530-536 (1999). |