Bioactivity | AF 698 is a phthalate derivative of apovincamine that can be used as a peripheral vasodilator with selective vasomotor effects on cerebral microvascular circulation. AF 698 has lower acute toxicity and better vasodilator effect than Vincamine (HY-B1021), but there is no significant difference in the protective effect of the two drugs against hypobaric hypoxia-induced lethality in mice[1]. |
CAS | 82958-11-0 |
Formula | C28H26N2O4 |
Molar Mass | 454.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Marzo, et al. A new phthalidyl derivative of apovincaminic acid:(3 alpha, 16 alpha)-eburnamenine-14 carboxylic acid phthalidyl ester (AF 698). A preliminary report on its chemical and pharmacological properties. Arzneimittel-forschung 32.6 (1982): 601-603. |