AEP-IN-3_product_DataBase

CAS: 2978521-26-3 F: C21H21F4N3O4 W: 455.40

AEP-IN-3 (compound 18) is an orally active, potent and brain penetrant asparagine endopeptidase (AEP) inhibitor, with an

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	AEP-IN-3 (compound 18) is an orally active, potent and brain penetrant asparagine endopeptidase (AEP) inhibitor, with an IC50 of 7.8 ± 0.9 nM. AEP-IN-3 can be used for Alzheimer’s Disease (AD) research[1].
In Vivo	AEP-IN-3 (compound 18) 的生物利用度为 83%，T1/2
Name	AEP-IN-3
CAS	2978521-26-3
Formula	C21H21F4N3O4
Molar Mass	455.40
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Krummenacher D, et al. Discovery of Orally Available and Brain Penetrant AEP Inhibitors. J Med Chem. 2023 Dec 28;66(24):17026-17043.

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