Bioactivity | AE-ITU dihydrobromide is the dihydrobromide form of AE-ITU. AE-ITU dihydrobromide is a selective inhibitor for inducible NO synthase (iNOS), and attenuates the liver dysfunction caused by endotoxaemia in rats[1]. |
In Vivo | AE-ITU dihydrobromide (1 mg/kg/h,静脉注射,持续 1 小时) 可减轻 LPS (HY-D1056) 诱导的 Wistar 大鼠迟发性低血压和血管反应性低下,改善肝功能障碍[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
CAS | 56-10-0 |
Formula | C3H11Br2N3S |
Molar Mass | 281.01 |
Appearance | 固体 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Reference | [1]. Thiemermann C, et al., The multiple organ dysfunction syndrome caused by endotoxin in the rat: attenuation of liver dysfunction by inhibitors of nitric oxide synthase. Br J Pharmacol. 1995 Dec;116(7):2845-51. |