| Bioactivity | ADPRP is an intranuclear enzyme whose main activity is to use NAD+ (nicotinamide adenine dinucleotide) as a substrate to add ADP-ribose units to chromatin-bound proteins, including the ADPRP enzyme itself. This process, called poly(ADP-ribosylation), is a post-translational modification that regulates the interaction between DNA and nuclear proteins[1]. |
| CAS | 53595-18-9 |
| Formula | C15H24N5O17P3 |
| Molar Mass | 639.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yamanaka H, et al. Human autoantibodies to poly (adenosine diphosphate-ribose) polymerase[J]. The Journal of clinical investigation, 1987, 80(3): 900-904. |