| Bioactivity | AD16 (Acetamide) is a LINE-1 retrotransposon endonuclease inhibitor with the IC50 of 4.7 μM. AD16 (Acetamide) reduce LINE-1 retrotransposition, L1-induced DNA damage, and inflammation reinforced by L1 in senescent cells[1]. |
| CAS | 311315-04-5 |
| Formula | C24H20N14O3S2 |
| Molar Mass | 616.64 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. D'Ordine AM, et al. Identification and characterization of small molecule inhibitors of the LINE-1 retrotransposon endonuclease. Nat Commun. 2024;15(1):3883. Published 2024 May 8. |