| Bioactivity | AChE/BChE/MAO-B-IN-2 is a potent AChE, BChE, and MAO-B enzymes inhibitor with IC50 values of 48.2 nM, 83.9 nM, and 31.2 nM, respectively. AChE/BChE/MAO-B-IN-2 has significant antioxidant activity, and can be used for Parkinson’s disease research[1]. |
| Invitro | AChE/BChE/MAO-B-IN-2 (compound D37) 具有 DPPH 自由基清除活性，IC50 为 0.179 μM。AChE/BChE/MAO-B-IN-2 还具有抑制 β-淀粉样蛋白聚集的能力[1]。 |
| Name | AChE/BChE/MAO-B-IN-2 |
| Formula | C25H31N3O3 |
| Molar Mass | 421.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Begüm Nurpelin Sağlık, et al. Design, Synthesis, and In Vitro and In Silico Approaches of Novel Indanone Derivatives as Multifunctional Anti-Alzheimer Agents. ACS Omega. 2022 Dec 7;7(50):47378-47404. |