| Bioactivity | AChE/BChE/MAO-B-IN-1 (Compound 10) is a reversible and non-time-dependent AChE, BChE and MAO-B inhibitor with IC50 values of 7.31, 0.56 and 26.1 μM for hAChE, hBChE and hMAO-B, respectively. AChE/BChE/MAO-B-IN-1 can cross the BBB and shows neuroprotective effects without cytotoxicity[1]. |
| Invitro | AChE/BChE/MAO-B-IN-1 (Compound 10) prevents amyloid β1-42 (Aβ1-42)-induced neuronal cell death[1]. |
| Name | AChE/BChE/MAO-B-IN-1 |
| CAS | 2416910-82-0 |
| Formula | C20H24N2O2 |
| Molar Mass | 324.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Košak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 Jul 1;197:112282. |
AChE/BChE/MAO-B-IN-1
CAS: 2416910-82-0 F: C20H24N2O2 W: 324.42
AChE/BChE/MAO-B-IN-1 (Compound 10) is a reversible and non-time-dependent AChE, BChE and MAO-B inhibitor with IC50 value
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.