| Bioactivity | BACE1-IN-15 (compound 4j) is a potent inhibitor of BACE1 (β-secretase) that can inhibited the copper ion induced Aβ toxicity, with the EC50 of 0.68 μM[1]. |
| Formula | C20H17F3N4O |
| Molar Mass | 386.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lin-Jie Tan, et al. Discovery of cinnamamide/ester triazole hybrids as potential treatment for Alzheimer’s disease. Bioorganic Chemistry Volume 150, September 2024, 107584. |