| Bioactivity | ACG548B (compound 24) is a potent inhibitor of acetyl- and butyrylcholinesterase (AChE and BChE) with IC50s of 1.78 and 0.496 μM, respectively. ACG548B has higher AChE affinity and selectivity over BChE and ChoK (choline kinase)[1]. |
| Target | BChE; ChoK |
| Name | ACG548B |
| CAS | 795316-16-4 |
| Formula | C38H34Br2Cl2N4 |
| Molar Mass | 777.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Conejo-García A, et al. Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity. J Med Chem. 2011 |
ACG548B
CAS: 795316-16-4 F: C38H34Br2Cl2N4 W: 777.42
ACG548B (compound 24) is a potent inhibitor of acetyl- and butyrylcholinesterase (AChE and BChE) with IC50s of 1.78 and
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.