| Bioactivity | ABT-770 (compound 11) is a highly selective and orally active MMP inhibitor, demonstrating over 1000-fold selectivity for MMP-2 (IC50=4 nM) compared to MMP-1 (IC50=4600 nM). ABT-770 can be utilized in studies related to tumor growth, invasion, and metastasis[1]. |
| CAS | 220614-50-6 |
| Formula | C22H22F3N3O6 |
| Molar Mass | 481.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Curtin, et al. "Discovery and characterization of the potent, selective and orally bioavailable MMP inhibitor ABT-770." Bioorganic & medicinal chemistry letters 11.12 (2001): 1557-1560. |
ABT-770
CAS: 220614-50-6 F: C22H22F3N3O6 W: 481.42
ABT-770 (compound 11) is a highly selective and orally active MMP inhibitor, demonstrating over 1000-fold selectivity fo
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