| Bioactivity | ABCG2-IN-4 (Compound K31) is an orally active inhibitor for ABCG2, which reduces the release of Protoporphyrin IX (PPIX) (HY-B1247) from erythrocytes into plasma, and prevents the reduces phototoxicity. ABCG2-IN-4 exhibits anti-inflammatory and antioxidant activity in mouse models[1]. |
| CAS | 2559759-63-4 |
| Formula | C24H32N4O4 |
| Molar Mass | 440.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhu J, et al., Inhibition of ABCG2 prevents phototoxicity in a mouse model of erythropoietic protoporphyria. Nat Commun. 2024 Dec 4;15(1):10557. |
ABCG2-IN-4
CAS: 2559759-63-4 F: C24H32N4O4 W: 440.54
ABCG2-IN-4 (Compound K31) is an orally active inhibitor for ABCG2, which reduces the release of Protoporphyrin IX (PPIX)
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This product is for research use only, not for human use. We do not sell to patients.