Bioactivity | ABCG2-IN-2 is a potent ABCG2 inhibitor with favorable oral pharmacokinetic profiles in mice. ABCG2-IN-2 can be used for the research of tumor multidrug resistance (MDR) and erythropoietic protoporphyria (EPP)[1]. |
Name | ABCG2-IN-2 |
CAS | 2559759-59-8 |
Formula | C25H34N4O4 |
Molar Mass | 454.56 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhu J, et al. Metabolism-guided development of Ko143 analogs as ABCG2 inhibitors. Eur J Med Chem. 2023 Nov 5;259:115666. doi: 10.1016/j.ejmech.2023.115666. Epub 2023 Jul 20. |