| Bioactivity | ABC44 is a potent serine hydrolase inhibitor with IC50s of 0.1 μM and 6.5 μM for palmitoyl protein thioesterase 1 (PPT1) in situ and in vitro, respectively. ABC44 can be used for researching infantile neuronal ceroid lipofuscinosis[1]. |
| Target | IC50: 0.1 μM (PPT1 in situ), 6.5 μM (PPT1 in vitro) |
| Name | ABC44 |
| CAS | 1831135-46-6 |
| Formula | C31H40N6O5 |
| Molar Mass | 576.69 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cognetta AB 3rd, Niphakis MJ, Lee HC, Martini ML, Hulce JJ, Cravatt BF. Selective N-Hydroxyhydantoin Carbamate Inhibitors of Mammalian Serine Hydrolases. Chem Biol. 2015 Jul 23;22(7):928-37. |