| Bioactivity | AASS-IN-1 (Compound S-105) is an AASS (2-aminoadipic semialdehyde synthase) inhibitor with an IC50 value of 142 μM. AASS-IN-1 inhibits AASS activity by binding to the LOR domain of AASS. AASS-IN-1 holds potential for research in the field of hyperlysinemia[1]. |
| Target | IC50：142 μM (AASS) |
| Formula | C15H20ClN3O2 |
| Molar Mass | 309.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Leandro J, et al. Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1. Open Biol. 2022 Sep;12(9):220179. |