PeptideDB

AAL-149

CAS: 177258-60-5 F: C18H31NO2 W: 293.44

AAL-149 is a FTY720 (HY-12005) analog and TRPM7 inhibitor (IC50 = 1.081 μM) with multimodal anti-inflammatory effects a
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Bioactivity AAL-149 is a FTY720 (HY-12005) analog and TRPM7 inhibitor (IC50 = 1.081 μM) with multimodal anti-inflammatory effects and without targeting S1P receptors. AAL-149 can be utilized in anti-inflammatory research[1].
CAS 177258-60-5
Formula C18H31NO2
Molar Mass 293.44
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Busey GW, et al. Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects. J Gen Physiol. 2024 Jan 1;156(1):e202313419.