Bioactivity | AAL-149 is a FTY720 (HY-12005) analog and TRPM7 inhibitor (IC50 = 1.081 μM) with multimodal anti-inflammatory effects and without targeting S1P receptors. AAL-149 can be utilized in anti-inflammatory research[1]. |
CAS | 177258-60-5 |
Formula | C18H31NO2 |
Molar Mass | 293.44 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Busey GW, et al. Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects. J Gen Physiol. 2024 Jan 1;156(1):e202313419. |