| Bioactivity | AAE871 is a potent type I FLT3 inhibitor with an IC50 value of 0.034 µM. AE871 has the potential for the research of acute myeloid leukemia (AML) [1]. |
| Target | IC50: 0.034 µM (FLT3) |
| CAS | 289479-07-8 |
| Formula | C24H34N8O2S |
| Molar Mass | 498.64 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Weisberg E, et al. Antileukemic Effects of Novel First- and Second-Generation FLT3 Inhibitors: Structure-Affinity Comparison. Genes Cancer. 2010 Oct;1(10):1021-32. |