| Bioactivity | A3AR agonist 2 (Compound 19) a selective A3AR agonist (Ki: 22.1 nM). A3AR agonist 2 stimulates β-arrestin2 recruitment, with EC50 value of 4.36 nM. A3AR agonist 2 can be used for research of inflammatory diseases, ischemia, cancer, neuropathic pain, liver diseases, and other chronic conditions[1]. |
| Target | Ki: 22.1 nM (A3AR) |
| Name | A3AR agonist 2 |
| Formula | C34H34N6O6 |
| Molar Mass | 622.67 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dilip K. Tosh, et al. First Potent Macrocyclic A3 Adenosine Receptor Agonists Reveal G-Protein and 尾-Arrestin2 Signaling Preferences. ACS Pharmacol. Transl. Sci. 2023. |