| Bioactivity | A-65317 is a primate-selective renin dipeptide inhibitor (IC50 of 0.37 nM) with long hypotensive response[1][2]. |
| CAS | 122224-84-4 |
| Formula | C38H58N6O9 |
| Molar Mass | 742.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. K M Verburg, et al. Effect of intrarenal renin inhibition on renal hemodynamics and excretory function. Am J Physiol. 1990 Jul;259(1 Pt 2):R7-14. [2]. Saul H. Rosenberg, et al. Renin Inhibitors. Integration of Pharmaceutical Discovery and Development Chapter pp 7-28. |