| Bioactivity | A-425619, a potent and selective TRPV1 receptor antagonist, is effective in alleviating acute and chronic inflammatory pain and postoperative pain[1]. |
| In Vivo | A-425619 (i.p., 100 μmoL/kg) 可以恢复弗氏完全佐剂（CFA；10 mg/mL）诱导的膝关节炎症引起的 C57BL/6J 小鼠自发挖掘行为的减少[1]。 |
| Name | A-425619 |
| CAS | 581809-67-8 |
| Formula | C18H14F3N3O |
| Molar Mass | 345.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sampurna Chakrabarti, et al. Acute inflammation sensitizes knee-innervating sensory neurons and decreases mouse digging behavior in a TRPV1-dependent manner. Neuropharmacology. 2018 Dec;143:49-62. |
A-425619
CAS: 581809-67-8 F: C18H14F3N3O W: 345.32
A-425619, a potent and selective TRPV1 receptor antagonist, is effective in alleviating acute and chronic inflammatory p
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