| Bioactivity | A-123189 is a selective and potent α1D antagonist with Kis of 0.312 and 0.17 for human α1D and rat α1D, respectively. A-123189 displays selectivities between 10- to 20-fold for the α1D receptor over the human α1A and rat α1A receptors[1]. |
| Name | A-123189 |
| CAS | 255713-53-2 |
| Formula | C26H28N4O3S |
| Molar Mass | 476.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. K P Briski, et al. Antagonism of type II, but not type I glucocorticoid receptors results in elevated basal luteinizing hormone release in male rats. Bioorganic & Medicinal Chemistry Letters, Volume 11, Issue 9, 7 May 2001, Pages 1119-1121. |