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9-cis-Retinol acetate-d5

CAS: 1217219-62-9 F: C22H27D5O2 W: 333.52

9-cis-Retinol acetate-d5 is the deuterium labeled 9-cis-Retinol acetate. 9-cis-Retinol acetate is a retinal derivative.
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Bioactivity 9-cis-Retinol acetate-d5 is the deuterium labeled 9-cis-Retinol acetate. 9-cis-Retinol acetate is a retinal derivative[1][2].
Invitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name 9-cis-Retinol acetate-d5
CAS 1217219-62-9
Formula C22H27D5O2
Molar Mass 333.52
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Hussain RM, Gregori NZ, Ciulla TA, Lam BL. Pharmacotherapy of retinal disease with visual cycle modulators. Expert Opin Pharmacother. 2018;19(5):471-481.