Bioactivity | 9-Methylstreptimidone is a microbial metabolite originally isolated from Streptomyces sp. S-885 that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus (MICs=4-20 μg/mL) and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro (MIC=0.02 μg/mL for all). 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection. |
CAS | 51867-94-8 |
Formula | C17H25NO4 |
Molar Mass | 307.38 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Saito, et al. Studies on a new antiviral antibiotic, 9-methylstreptimidone. I. Physicochemical and biological properties. J. Antibiot. (Tokyo) 27(3), 206-214 (1974). |