| Bioactivity | 9-Cyclopentyladenine monomethylsulfonate (9-CP-Ade mesylate) is a stable non-competitive adenylate cyclase inhibitor with cell permeable properties[1][2]. |
| Invitro | 9-Cyclopentyladenine monomethanesulfonate (200 μM, 30 min) inhibits the activation of cAMP response element binding protein (CREB) and completely blocks neurogenesis in PC12 cells[1].9-Cyclopentyladenine monomethanesulfonate (100 μM, 30min) attenuates the effect of relaxin on mechanical activity and prevents relaxin-induced hyperpolarization thereby being involved in the regulation of relaxin on ileal smooth muscle activity in female CD1 Swiss mice[2].9-Cyclopentyladenine monomethanesulfonate (100 μM, 6 hours) promotes restoration of the keratinocyte permeability barrier by inhibiting the synthesis of cAMP in male hairless mice[3]. |
| Name | 9-Cyclopentyladenine monomethanesulfonate |
| CAS | 189639-09-6 |
| Formula | C11H17N5O3S |
| Molar Mass | 299.35 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Ulrike Riese，et al. Militarinone A induces differentiation in PC12 cells via MAP and Akt kinase signal transduction pathways. FEBS Lett. 2004 Nov 19;577(3):455-9. [2]. Eglantina Idrizaj，et al. Relaxin influences ileal muscular activity through a dual signaling pathway in mice. World J Gastroenterol. 2018 Feb 28;24(8):882-893. [3]. Mitsuhiro Denda, et al. Association of cyclic adenosine monophosphate with permeability barrier homeostasis of murine skin. J Invest Dermatol. 2004 Jan;122(1):140-6. |
9-Cyclopentyladenine monomethanesulfonate
CAS: 189639-09-6 F: C11H17N5O3S W: 299.35
9-Cyclopentyladenine monomethylsulfonate (9-CP-Ade mesylate) is a stable non-competitive adenylate cyclase inhibitor wit
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