9,10-trans-Dehydroepothilone D_product_DataBase

CAS: 350493-61-7 F: C27H39NO5S W: 489.67

9,10-trans-Dehydroepothilone D shows an antiproliferative activity against a paclitaxel-resistant cell lines overexpress

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	9,10-trans-Dehydroepothilone D shows an antiproliferative activity against a paclitaxel-resistant cell lines overexpressing P-glycoprotein. 9,10-trans-Dehydroepothilone D also shows tubulin polymerization activity. 9,10-trans-Dehydroepothilone D is given by lactonization of Seco acid, which is promising for research of cancers[1].
CAS	350493-61-7
Formula	C27H39NO5S
Molar Mass	489.67
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. White JD, et al. Total synthesis of epothilone B, epothilone D, and cis- and trans-9,10-dehydroepothilone D. J Am Chem Soc. 2001 Jun 13;123(23):5407-13.

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