| Bioactivity | 8-pCPT-cGMP-AM (8-(4-Chlorophenylthio)-cGMP-AM) is a highly membrane permeable prodrug of the PKG agonist 8-pCPT-cGMP, which increases the membrane permeability of cGMP and is converted to its active form by esterase hydrolysis within the cell, thereby activating PKG. 8-pCPT-cGMP-AM can be used to explore the role of cGMP signaling in neural plasticity and memory formation[1]. |
| CAS | 272445-72-4 |
| Formula | C19H19ClN5O9PS |
| Molar Mass | 559.87 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Butt E. cGMP-dependent protein kinase modulators[J]. cGMP: Generators, Effectors and Therapeutic Implications, 2009: 409-421. |
8-pCPT-cGMP-AM
CAS: 272445-72-4 F: C19H19ClN5O9PS W: 559.87
8-pCPT-cGMP-AM (8-(4-Chlorophenylthio)-cGMP-AM) is a highly membrane permeable prodrug of the PKG agonist 8-pCPT-cGMP, w
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