Bioactivity | 8-Nitroguanine, a product of nitrative DNA damage caused by reactive nitrogen species, is a potential biomarker for progression of malignant fibrous histiocytoma[1][2]. |
Invitro | 与单次感染相比,反复的 Opisthorchis viverrini (OV) 感染增加了胆管上皮中 8-Nitroguanine 的形成和 iNOS 的表达。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> 8-Nitroguanine 相关抗体: |
CAS | 168701-80-2 |
Formula | C5H4N6O3 |
Molar Mass | 196.12 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hiroshi Ohshima, et al. 8-nitroguanine, a product of nitrative DNA damage caused by reactive nitrogen species: formation, occurrence, and implications in inflammation and carcinogenesis. Antioxid Redox Signal. 2006 May-Jun;8(5-6):1033-45. [2]. Yoko Hoki, et al. 8-Nitroguanine as a potential biomarker for progression of malignant fibrous histiocytoma, a model of inflammation-related cancer. Oncol Rep. 2007 Nov;18(5):1165-9. [3]. Yusuke Hiraku, et al. Formation of 8-nitroguanine, a nitrative DNA lesion, in inflammation-related carcinogenesis and its significance. Environ Health Prev Med. 2010 Mar;15(2):63-72. |