Bioactivity | 8-NBD-cAMP sodium is a fluorescently labeled cyclic adenosine phosphate (cAMP) analogue. 8-NBD-cAMP sodium retains a similar biological activity to cAMP, regulating their activity by binding to specific proteins such as EPACs or PKA. 8-NBD-cAMP sodium can be used in fluorescent competitive binding experiments to evaluate the binding affinity of newly synthesized EPAC1 agonists to EPAC1 proteins[1]. |
CAS | 221905-51-7 |
Formula | C18H17N9NaO9PS |
Molar Mass | 589.41 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wang P, et al. Synthesis and biochemical evaluation of noncyclic nucleotide exchange proteins directly activated by cAMP 1 (EPAC1) regulators[J]. Journal of medicinal chemistry, 2020, 63(10): 5159-5184. |