8-Br-PET-cGMP

CAS: 144510-04-3 F: C18H15BrN5O7P W: 524.22

8-Br-PET-cGMP is an agonist of cGMP-dependent protein kinase type I (cGKI). 8-Br-PET-cGMP promotes the dimerization of c

Contact QiTai

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	8-Br-PET-cGMP is an agonist of cGMP-dependent protein kinase type I (cGKI). 8-Br-PET-cGMP promotes the dimerization of cGKI and activates its catalytic activity by binding to the regulatory domain of cGKI. 8-Br-PET-cGMP can be used to study the role of cGMP signaling pathways in cell growth, vasodilation, and smooth muscle cell function[1].
CAS	144510-04-3
Formula	C18H15BrN5O7P
Molar Mass	524.22
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Valtcheva, et al. The commonly used cGMP-dependent protein kinase type I (cGKI) inhibitor Rp-8-Br-PET-cGMPS can activate cGKI in vitro and in intact cells. Journal of Biological Chemistry 284.1 (2009): 556-562.

(+)-Oxanthromicin