| Bioactivity | 7-tert-Butylfascaplysin (7-TB) is a derivative of Fascaplysin (HY-112328), that can be isolated from Fascaplysinopsis sp.. 7-tert-Butylfascaplysin induces replication stress, leads to toxic DNA double-strand breaks and apoptosis-like cell death, and thus exhibits cytotoxicity in cancer cells in nanomolar levels. 7-tert-Butylfascaplysin exhibits DNA intercalating activity with EC50 of 3.2 μM[1]. |
| Formula | C22H19ClN2O |
| Molar Mass | 362.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dyshlovoy SA, et al., Synthesis and new DNA targeting activity of 6- and 7-tert-butylfascaplysins. Sci Rep. 2024 May 23;14(1):11788. |
7-tert-Butylfascaplysin
CAS: F: C22H19ClN2O W: 362.85
7-tert-Butylfascaplysin (7-TB) is a derivative of Fascaplysin (HY-112328), that can be isolated from Fascaplysinopsis sp
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